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Eutylone and pentylone inhibited uptake at serotonin transporters (SERT), although dibutylone did not. Also, eutylone and pentylone exhibited weak partial releasing steps at SERT which achieved 50% of maximal response. All drugs stimulated dose-linked locomotion in mice, and eutylone was most potent and efficacious in this regard (ED50 = two mg/kg,